WHO Hyperplasia-EIN Concordance

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Because EIN lesions are diagnosed using different criteria than WHO hyperplasias, the correlation is not fixed.   Colored portions of Bar Graphs show approximate percentages of each WHO hyperplasia class that will be diagnosed as EIN.  Remaining WHO hyperplasias not diagnostic of EIN (gray) will be allocated to unopposed estrogen (anovulatory), polyp, and other benign categories.  Pie chart shows relative contributions of each hyperplasia type to the EIN diagnostic category in a biopsy series of sequential endometrial hyperplasias seen in a busy hospital practice.  (Mutter, Baak, and Hecht, 2003)

Atypical hyperplasias rediagnosed as EIN

Complex non-atypical hyperplasias rediagnosed as EIN

Simple non-atypical hyperplasias rediagnosed as EIN

Hyperplasias not diagnosed as EIN

 

 

 

 

 

 

Atypical hyperplasias rediagnosed as EIN 70, 79, 616, 755,

 d070_08.jpg (68876 bytes) d079_03.jpg (97687 bytes) d616_02.jpg (102923 bytes) d755_04.jpg (94425 bytes)

Complex Non-Atypical hyperplasias rediagnosed as EIN 59956, 59102

Simple non-atypical hyperplasias rediagnosed as EIN 208, 342, 632, 996

d208_05.jpg (91006 bytes) d342_04.jpg (107887 bytes) d632_04.jpg (94177 bytes) d996_03.jpg (87627 bytes)

Hyperplasias not diagnosed as EIN

Atypical hyperplasia rediagnosed as anovulatory 523, 945

d523_02.jpg (96692 bytes) d945_02.jpg (80266 bytes)

Atypical hyperplasia rediagnosed as menstrual 129, 298, 453

d129_04.jpg (94237 bytes) d298_04.jpg (99115 bytes) d453_03.jpg (92450 bytes)

Atypical hyperplasia rediagnosed as Polyp 290, 120, 847, 950

d290_03.jpg (111159 bytes) d120_01.jpg (61166 bytes) d847_03.jpg (98674 bytes) d950_02.jpg (81002 bytes)

Atypical hyperplasia rediagnosed as Normal (Proliferative basalis)  16

d016_03.jpg (99385 bytes)

Simple Non-atypical Hyperplasia rediagnosed as Polyp 4, 101, 155, 464, 603, 642, 665

d004_02.jpg (82247 bytes) d101_02.jpg (91005 bytes) d155_02.jpg (77331 bytes) d464_02.jpg (90178 bytes) d603_04.jpg (106550 bytes) d642_02.jpg (90050 bytes) d665_02.jpg (53092 bytes)

Simple Non-atypical Hyperplasia rediagnosed as Anovulatory 62, 132, 171, 173, 223, 368, 427, 436, 578, 605, 664, 679, 756

d062_02.jpg (75123 bytes) d132_03.jpg (91411 bytes) d171_02.jpg (78244 bytes) d173_02.jpg (76444 bytes) d223_03.jpg (103365 bytes) d368_03.jpg (111473 bytes) d427_03.jpg (105011 bytes) d436_02.jpg (117667 bytes) d578_03.jpg (89568 bytes) d605_02.jpg (73793 bytes) d664_02.jpg (95782 bytes) d679_03.jpg (91173 bytes) d756_03.jpg (96345 bytes)

Simple Non-atypical Hyperplasia rediagnosed as Normal Proliferative  268, 581, 753, 762, 765, 993

d268_08.jpg (102916 bytes) d581_02.jpg (124666 bytes) d753_06.jpg (105266 bytes) d762_02.jpg (105426 bytes) d765_02.jpg (116857 bytes) d993_03.jpg (98066 bytes)

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Copyright 1998-2015 by George L. Mutter, MD.  All Rights Reserved